Face tightening without filler - Collagen stimulators

Polynucleotides – Collagen Stimulators

Polynucleotides are an advanced injectable skin regeneration treatment designed to repair, hydrate and revitalise the skin at a cellular level. Rather than adding volume, polynucleotides work by stimulating your skin’s natural repair processes, improving overall skin quality, elasticity and tone.

At Ozone clinics, we use polynucleotides to help restore tired, damaged or ageing skin, delivering subtle, natural-looking rejuvenation from within.

What are Polynucleotides

Polynucleotides are naturally derived molecules that support cell regeneration, collagen production and tissue repair. When injected into the skin, they act as bio-stimulators, encouraging healthier skin structure and long-term improvement.

This treatment is ideal for clients seeking skin rejuvenation without dermal fillers, focusing on skin quality rather than volume.

How Do Polynucleotides Improve Skin Quality?

Polynucleotides work as bio-stimulators. Once injected into the skin, they encourage collagen production, improve hydration, and support tissue repair. Rather than adding volume like dermal fillers, they focus on improving overall skin texture, elasticity, and tone.

How Many Treatments Will I Need?

Most patients benefit from a course of two to three treatments spaced a few weeks apart. This allows the regenerative effects to build gradually. Your clinician will recommend a tailored plan based on your skin condition and goals.

How Long Do Results Last?

Results develop gradually over several weeks as collagen production increases. Many patients choose maintenance treatments every six to nine months to maintain skin quality improvements.

Is There Any Downtime After Treatment?

Downtime is usually minimal. You will probably experience mild swelling, redness, and / or small injection marks for a few days. Bruising can occasionally occur. Most patients return to normal activities quickly.

Can Polynucleotides Be Used Under The Eyes?

Yes. Polynucleotides are particularly suitable for delicate areas such as the under-eye region, neck, and décolletage. They are often chosen for thin or crepey skin where subtle rejuvenation is preferred.

Is The Treatment Painful?

The injections are generally well tolerated. A topical numbing cream can be applied beforehand to improve comfort. Most patients describe the treatment as mildly uncomfortable rather than painful.

Who Is Suitable For Polynucleotide Treatments?

Polynucleotides are suitable for adults looking to improve skin quality, including those concerned about early ageing, dull skin, acne scarring, or thinning skin. A consultation is essential to determine suitability, particularly for those with medical conditions or who are pregnant or breastfeeding.

Are Polynucleotides Safe?

When performed by trained medical professionals, polynucleotide treatments are considered safe and well tolerated. As with any injectable treatment, there are potential risks, which will be discussed during your consultation.